Table 1 Pathogenic roles of lncRNA TUG1 in colorectal cancer
From: The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer
Axis | Cell line (in vitro) | Animal model (in vivo) | Patients-derived tissue | Cancer Chemo-resistance | Cancer initiation (cell proliferation) | Cancer progression | Cancer metastasis | Cancer apoptosis | Refs. |
|---|---|---|---|---|---|---|---|---|---|
miR-145-5p/TRPC6 | ✓ | ✓ | ✓ | --- | ✓ | ✓ | --- | --- | [42] |
miR-138-5p/ZEB2 | ✓ | --- | ✓ | --- | --- | ✓ | ✓ | --- | [43] |
Wnt/β-catenin | ✓ | ✓ | ✓ | --- | ✓ | --- | --- | --- | [46] |
GATA6/BMP | ✓ | ✓ | --- | ✓ | --- | --- | --- | ✓ | [67] |
miR-153-1/KLF4 | ✓ | ✓ | ✓ | ---- | ✓ | --- | ✓ | --- | [60] |
miR-186/CPEB2 | ✓ | --- | ✓ | ✓ | --- | --- | --- | ✓ | [69] |
TGF-β/TWIST1 | ✓ | ✓ | ✓ | --- | --- | --- | ✓ | --- | [49] |
miR-197-3p/TYMS | ✓ | ✓ | ✓ | ✓ | ✓ | --- | --- | ✓ | [65] |
miR-421/KDM2A/ERK/SP1 | ✓ | ✓ | ✓ | --- | --- | ✓ | --- | ✓ | [51] |
miR-542-3p/TRIB2/Wnt/β-catenin | ✓ | ✓ | ✓ | --- | ✓ | ✓ | --- | ✓ | [58] |
miR-195-5p/IGF2BP2 | ✓ | ✓ | ✓ | ✓ | --- | --- | --- | --- | [73] |