Table 4 The overall response rate and disease control rate in the SWI/SNF-mutant and SWI/SNF-non-mutant groups
Cancer type | SWI/SNF-mutant | SWI/SNF-non-mutant | p for ORR | p for DCR | ||||
|---|---|---|---|---|---|---|---|---|
n | ORR (%) | DCR (%) | n | ORR (%) | DCR (%) | |||
Total | 301 | 3.32 | 80.07 | 700 | 0.43 | 65.57 | 0.0002 |  < 0.0001 |
Breast cancer | 4 | 0 | 25.00 | 15 | 0 | 40.00 | 0.9999 | 0.9999 |
Cervical cancer | 6 | 0 | 50.00 | 25 | 4.00 | 64.00 | 0.9999 | 0.6526 |
colorectal cancer | 102 | 4.90 | 86.27 | 115 | 0.87 | 67.83 | 0.1016 | 0.0014 |
Endometrial cancer | 17 | 0 | 64.71 | 16 | 0 | 75.00 | 0.9999 | 0.7080 |
Esophagus cancer | 6 | 0 | 50.00 | 17 | 0 | 47.06 | 0.9999 | 0.9999 |
Gallbladder and Biliary tract cancer | 6 | 0 | 50.00 | 11 | 0 | 90.91 | 0.9999 | 0.0987 |
Gastric cancer | 24 | 0 | 83.33 | 52 | 0 | 55.77 | 0.9999 | 0.0222 |
kidney cancer | 5 | 0 | 100.00 | 7 | 0 | 71.43 | 0.9999 | 0.4697 |
Liver cancer | 7 | 0 | 100.00 | 27 | 0 | 74.07 | 0.9999 | 0.2997 |
Melanoma | 8 | 12.50 | 62.50 | 74 | 0 | 50.00 | 0.0976 | 0.7130 |
Non-small cell lung cancer | 67 | 2.99 | 85.07 | 190 | 0.53 | 71.58 | 0.1674 | 0.0324 |
Other | 16 | 12.50 | 81.25 | 62 | 0 | 69.35 | 0.0400 | 0.5345 |
Ovarian and Fallopian tube cancer | 6 | 0 | 66.67 | 12 | 0 | 50.00 | 0.9999 | 0.6380 |
Pancreatic cancer | 4 | 0 | 100.00 | 13 | 0 | 69.23 | 0.9999 | 0.5193 |
Prostatic cancer | 1 | 0 | 100.00 | 5 | 0 | 60.00 | 0.9999 | 0.9999 |
Small cell lung cancer | 1 | 0 | 100.00 | 12 | 0 | 66.67 | 0.9999 | 0.9999 |
Soft tissue sarcoma | 4 | 0 | 50.00 | 19 | 0 | 52.63 | 0.9999 | 0.9999 |
Urothelial cancer | 17 | 0 | 76.47 | 28 | 0 | 82.14 | 0.9999 | 0.7109 |