Fig. 2
From: RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC
RBM10 inhibits invasion and metastasis of A549 and H1299 cells. A A549 and H1299 cells were transfected with lentiviruses expressing GV358-RBM10 (oe-RBM10), GV248-RBM10 (sh-RNA), and negative control (oe-NC and sh-NC). Using Western blot, total protein extracts were analyzed for RBM10 expression; negative control served as control respectively. B The effect of RBM10 on cell invasion was measured using the transwell invasion assay (200 ×). C The effect of RBM10 on cell metastasis was measured using the scratch test (40 ×). D The effect of RBM10 on the expression of N-cadherin, vimentin, and E-cadherin was measured using Western blotting analysis. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Data are means ± SD