Fig. 4
From: RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC
RBM10 regulates Neat1 AS. A Clip-seq analysis revealed the top 10 LncRNA binding sites in the RBM10 binding peak according to maxHeight. B RIP assay to verify the binding between RBM10 and Neat1. C Neat1 expression in A549 cells after RBM10 overexpressing and silencing by RT-qPCR, normalized to β-actin. D Structure of NEAT1_1 and Neat1_2 and binding site of RBM10 to Neat1. E RIP assay to verify the binding between RBM10 and Neat1_2. F Neat1_2 expression in A549 cells after RBM10 overexpressing and silencing by RT-qPCR, normalized to β-actin. G Proportion of Neat_2 in total Neat1 after RBM10 overexpressing and silencing. H. Neat1_1 expression in A549 cells after RBM10 overexpressing and silencing. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Data are means ± SD