Fig. 7
From: RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC
RBM10 regulated PTEN/PI3K/AKT/mTOR signaling pathway via Neat1_2 in NSCLC cells. A PTEN protein expression after silencing Neat1 in RBM10-silenced A549 cells by Western blot analysis, normalized to GAPDH. B PTEN protein expression after silencing Neat1 in RBM10-silenced A549 cells by cell immunofluorescence assay. C The phosphorylation of PI3K, AKT, and mTOR after silencing Neat1 in RBM10-silenced A549 cells by western blot analysis, normalized to GAPDH. *p < 0.05, **p < 0.01, ***p < 0.001. Data are means ± SD