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Fig. 2 | Cancer Cell International

Fig. 2

From: Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model

Fig. 2

Expression of A–E hepatic caspase-3, Bax, Bcl-2, Bax/ Bcl-2 ratio and Bcl-XL mRNA, respectively; F Serum circulating miR-21 of non-carcinogenic and carcinogenic male albino rats treated with either pomegranate juice (PJ) or punicalagin (PCG). Values were presented as fold changes after normalization with the expression of a housekeeping miRNA (miR-U16) or a housekeeping gene (GAPDH: glyceraldehyde-3phosphate dehydrogenase) for mRNA. HCC: hepatocellular carcinogenic-induced group. *, ** and ***: P < 0.05, P < 0.01 and P < 0.001, respectively, compared to control group; #, ## and ###: P < 0.05, P < 0.01 and P < 0.001compared to carcinogenic control group

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Cancer Cell International

ISSN: 1475-2867

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