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Table 1 Body-weight, Liver weight, Liver relative weight and biochemical indices of control and carcinogenic male albino rats treated with either pomegranate juice (PJ) or punicalagin (PCG)

From: Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model

Group

Non-carcinogenic groups

Carcinogenic groups

Control

PJ

(10 mL/ kg b.w)

PCG

(18.5 mg/ kg b.w)

HCC

(50 mg DENA/ kg b.w)

HCC

(50 mg DENA/kg b.w)

 + 

PJ(10 mL/ kg b.w)

HCC

(50 mg DENA/ kg b.w)

 + 

PCG (18.5 mg/ kg b.w)

Body weight (g)

77.74 ± 2.72

65.62 ± 2.22*

63.10 ± 2.45**

21.40 ± 1.91***

47.80 ± 0.58***###

41.60 ± 3.37***###

Liver weight (g)

7.07 ± 0.10

7.30 ± 0.14

6.54 ± 0.24

6.06 ± 0.20*

6.68 ± 0.24

6.13 ± 0.21*

Liver relative weight

(g/ 100 g bw)

2.63 ± 0.25

2.89 ± 0.06

2.64 ± 0.07

3.25 ± 0.08 *

2.32 ± 0.03##

2.68 ± 0.19

ALAT (U/ mL)

6.83 ± 0.76

5.00 ± 0.48

11.45 ± 1.05*

19.21 ± 1.38***

8.23 ± 0.67###

16.44 ± 0.64***

Total protein (g/ dL)

8.58 ± 0.34

7.44 ± 0.28

7.08 ± 0.30*

6.17 ± 0.17***

8.37 ± 0.30###

6.77 ± 0.38**

  1. Data are presented as means and their standard error of means (n = 5 in each group). ALAT alanine aminotransferase; HCC hepatocellular carcinogenesis control group.
  2. *, ** and ***: P < 0.05, P < 0.01 and P < 0.001 (compared to control group)
  3. ##and ###: P < 0.01 and P < 0.001 (compared to HCC control group)
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Cancer Cell International

ISSN: 1475-2867

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