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Fig. 2 | Cancer Cell International

Fig. 2

From: CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway

Fig. 2

Hub genes in green and blue modules. A Go enrichment of green module. Top 5 significant pathways in different aspects. Circle represents biological process, triangle represents cellular component, rectangle represents molecular function. B Go enrichment of blue module. Top 5 significant pathways in different aspects. Circle represents biological process, triangle represents cellular component, rectangle represents molecular function. C, D KEGG enrichment of green and blue modules respectively. E, F Hub genes in green and blue modules respectively, which is calculated by the MCODE in Cytoscape. G Differential expressed genes in GSE10448. Up genes represent genes highly expressed in pancreatic cancer patients with lymph node metastasis. Down genes represent genes highly expressed in pancreatic cancer patients without lymph node metastasis. H 0 gene was derived from the intersection between hub genes in green module and up genes in GSE10448. I 13 genes were derived from the intersection between hub genes in blue module and down genes in GSE10448

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