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Fig. 1 | Cancer Cell International

Fig. 1

From: The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1

Fig. 1

ALKBH5 is upregulated in lung cancer tissues and associated with poor prognosis. A The expression levels of m6A modification-related genes in lung cancer tissues and normal tissues obtained by analyzing the TCGA database and GTEx database. B ALKBH5 expression in different tumors was analyzed using the TNM plot website. Tumors in red represent significant differences in expression levels between tumors and normal tissues. C Kaplan‒Meier analysis was used to show the correlation between ALKBH5 expression levels and overall survival of patients with lung cancer. D The expression of ALKBH5 was measured by qRT‒PCR in four lung cancer cell lines (A549, H1299, H1975, PC9) compared with the human bronchial epithelial cell 16HBE. *: P < 0.05, ***: P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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