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Fig. 2 | Cancer Cell International

Fig. 2

From: The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1

Fig. 2

Knockdown of ALKBH5 inhibits the proliferation and migration of lung cancer cells in vitro. A The knockdown efficiency in A549 and H1975 cells after transfection with ALKBH5 siRNAs or NC as shown by qRT‒PCR. B The protein expression level of ALKBH5 was detected in A549 and H1975 cells by western blot after transfection with ALKBH5 siRNAs or NC. C, D CCK-8 assays were performed to evaluate the proliferation of A549 and H1975 cells after knocking down ALKBH5. E, F Transwell assays were performed to evaluate migration in A549 and H1975 cells after knocking down ALKBH5. *: P < 0.05, **: P < 0.01, ***: P < 0.001

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