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Fig. 6 | Cancer Cell International

Fig. 6

From: Targeted blocking of CCR2 and CXCR2 improves the efficacy of transarterial chemoembolization of hepatocarcinoma

Fig. 6

CCR2 and CXCR2 antagonists inhibited HCC by reducing neutrophils and macrophages infiltration and HPCs activation. Rats were treated as in Fig. 5. Liver sections were prepared for immunohistochemical detection of CD68, MPO, and CK19. CK19 is a specific marker for hepatic progenitor cells. The positive area of each slice was quantified as average IOD with Image-Pro Plus software. A Representative images of CD68, MPO, and CK19 immunostaining in rat livers of the indicated groups. Scale bar, 200 μm. B–D Comparison of B CD68 levels, C MPO levels, and D CK19 levels of the indicated groups based on IOD results. Data are presented as mean ± SD. ns not statistically significant, ***p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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