Table 2 Univariate and multivariate analysis of the survival of patients with PBL

Age, years

0.052

5.243 (0.985–27.899)

0.061

4.621 (1.032–41.781)

0.049

3.169 (1.008–9.967)

0.882

1.150 (0.182–7.264)

  < 60

40

  ≥ 60

31

Ann arbor stage

0.402

0.708 (0.218–2.302)

0.844

0.937 (0.488–1.797)

 IE

39

 IIE

26

 IVE

6

 IPI

0.029

11.945 (1.281–111.394)

0.046

6.474 (1.021–41.145)

0.003

7.918 (1.993–31.454)

0.045

6.386 (1.043–39.090)

 0–1

45

 2–5

26

Pathological classification

0.671

0.637 (0.045–6.224)

0.781

0.653

(0.256–3.790)

 DLBCL

57

 Others

14

Pathology

0.796

0.739 (0.075–7.269)

0.800

0.808 (0.155–4.215)

 Non-GCB

29

 GCB

23

LDH

0.056

5.109 (0.958–27.259)

0.853

1.305 (0.078–21.773)

0.031

3.675 (1.075–12.566)

0.213

2.833 (0.549–14.616)

 Normal

34

 Elevated

26

β2-MG

0.384

2.413 (0.333–17.505)

0.758

1.245 (0.309–5.012)

 Normal

23

 Elevated

29

WBC

0.515

2.044 (0.237–17.632)

0.999

1.001 (0.128–7.841)

 Normal

61

 Elevated

3

Neut

0.993

0.993 (0.211–4.676)

0.532

0.699 (0.227–2.151)

 Normal

 Elevated

Lymph

0.684

0.632 (0.069–5.773)

0.752

1.252 (0.310–5.060)

 Normal

34

 Elevated

26

Ki-67 (%)

0.647

1.651 (0.192–14.172)

0.573

1.555 (0.335–7.220)

  < 50%

11

  ≥ 50%

57

c-Myc

0.942

1.032 (0.444–2.401)

0.22

1.1429 (0.807–2.529)

 Positive

23

 Negative

26

BCL-2

0.063

6.237 (0.905–42.995)

0.091

6.980 (0.639–45.946)

0.022

4.636 (1.246–17.255)

0.709

1.521 (0.168–13.729)

 Positive

40

 Negative

25

BCL-6

0.003

0.082 (0.015–0.431)

0.118

0.237 (0.039–1.439)

0.006

0.242 (0.088–0.670)

0.856

0.860 (0.169–4.379)

 Positive

34

 Negative

10

Double -hit-lymphomas

0.654

0.801 (0.213–2.008)

0.844

0.876 (0.479–1.135)

 Yes

23

 No

26

Unknown

22

Triple-hit- lymphomas

0.821

0.791 (0.158–2.548)

0.701

0.860 (0.178–2.901)

 Yes

16

 No

16

 Unknown

39

P53

0.947

1.026 (0.483–2.178)

0.821

0.938 (0.538–1.635)

 Positive

23

 Negative

23

CD30

0.858

0.909 (0.321–2.579)

0.236

0.670 (0.345–1.300)

 Positive

14

 Negative

27

CD5

0.088

0.254 (0.053–1.226)

0.326

0.403 (0.066–2.470)

0.017

0.361 (0.156–0.834)

0.365

0.511 (0.119–2.187)

 Positive

19

 Negative

32

EBER

0.639

0.410 (0.080–5.735)

0.972

0.963 (0.120–7.725)

 Positive

7

 Negative

51

Surgery

0.933

1.102 (0.115–10.540)

0.643

0.721 (0.180–2.878)

 Yes

44

 No

27

Rituximab given

0.092

2.632 (0.158–43.713)

0.549

2.907 (0.089–95.347)

0.091

2.602 (0.183–9.914)

0.702

0.850 (0.345–2.094)

 Yes

42

 No

13

RT

0.087

0.708 (0.267–1.877)

0.047

1.385 (0.201–9.550)

0.061

0.516 (0.258–1.031)

0.042

1.409 (0.024–8.148)

 Yes

9

 No

17