Fig. 4
From: Spatial metabolomics on liver cirrhosis to hepatocellular carcinoma progression
Metabolites’ spatial distributions in the non-cancer regions (CV) of the HC, LC and HCC samples under positive ionization mode. a HE and MSI images of the CV regions in the HC, LC and HCC samples. b PLS-DA analysis of the CV regions. c KEGG analysis of key altered metabolic pathways in the CV non-cancer regions. d Sample time series analysis of key metabolite expressions of the non-cancer regions. e Examples of key metabolites’ spatial expressions in the CV regions