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Table 1 The clinical data for liver cirrhosis and HCC participates

From: Spatial metabolomics on liver cirrhosis to hepatocellular carcinoma progression

Measurements

LC

HCC

Average

Referencea

Change

TP (g/L)

52.70

58.10

55.40 ± 2.70

63.00–79.00

↓

ALB (g/L)

34.80

39.80

37.30 ± 2.50

35.00–50.00

–

GLO (g/L)

17.90

18.30

18.10 ± 0.20

20.00–35.00

↓

A/G

1.94

2.17

2.06 ± 0.12

1.10–2.50

–

PA (mg/L)

83.00

152.00

117.50 ± 34.50

150.00–350.00

↓

TB (μmol/L)

41.30

194.80

118.10 ± 76.75

1.71–20.50

↑

GLD (U/L)

9.32

7.00

8.16 ± 1.16

 < 7.00

↑

DB (μmol/L)

11.00

70.00

40.50 ± 29.50

 < 5.10

↑

ID (μmol/L)

30.30

124.80

77.55 ± 47.25

3.40–12.00

↑

TBA (μmol/L)

140.00

136.60

138.30 ± 1.70

 < 10.00

↑

ALT (U/L)

31.00

37.00

34.00 ± 3.00

7.00–55.00

–

AST (U/L)

36.00

52.00

44.00 ± 8.00

8.00–48.00

–

GGT (U/L)

20.00

33.00

26.50 ± 6.50

8.00–61.00

–

ALP (U/L)

71.00

52.00

61.50 ± 9.50

40.00–129.00

–

CHE (U/L)

3704.00

2987.00

3346.00 ± 358.50

8k–18k

↓

LDH (U/L)

216.00

933.00

574.50 ± 358.50

140.00–280.00

↑

PT (S)

18.70

23.60

21.15 ± 2.45

11.00–13.50

↑

PT% (%)

51.00

36.00

43.50 ± 7.50

100.00

↓

PT INR

1.58

2.15

1.87 ± 0.29

0.80–1.10

↑

APTT (S)

55.00

40.80

47.90 ± 7.10

21.00–35.00

↑

FIB (g/L)

1.53

1.54

1.54 ± 0.01

2.00–4.00

↓

TT (s)

18.10

21.70

19.90 ± 1.80

14.00–19.00

↑

AT III (%)

39.00

41.00

40.00 ± 1.00

80.00–130.00

↓

D-DIC (μg/mL)

0.22

 > 20

10.11 ± 9.89

0.10–0.25

↑

AMON (μmol/L)

133.00

101.00

117.00 ± 16.00

11.00–32.00

↑

HBsAg

20.91 (+)

31.93 (+)

26.42 ± 5.51

N/A

N/A

HBsAb

0 (−)

0.99 (−)

0.50 ± 0.50

N/A

N/A

HBeAg

0.377 (+)

0.04 (−)

0.21 ± 0.17

N/A

N/A

HBeAb

1.54 (−)

0.01 (+)

0.78 ± 0.77

N/A

N/A

HBcAb

5.37 (+)

0.21 (−)

2.79 ± 2.58

N/A

N/A

Child–Pugh

9

13

11.00 ± 2.00

N/A

N/A

MELD

32

44

38.00 ± 6.00

N/A

N/A

  1. Averages are expressed as mean ± SEM
  2. TP, total protein; ALB, albumin; GLO, globulin; A/G, albumin/globulin ratio; PA, prealbumin; TB, total bilirubin; GLD, glutamate dehydrogenase; DB, direct bilirubin; ID, indirect bilirubin; TBA, total bile acid; ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transferase; ALP, alkaline phosphatase; CHE, cholinesterase; LDH, lactate dehydrogenase; PT, prothrombin time; INR, international normalized ratio; APTT, activated partial thromboplastin time; FIB, fibrinogen; TT, thrombin time; AT III, antithrombin III; D-DIC, D-dimer; AMON, ammonia; HBsAg, hepatitis B virus surface antigen; HBsAb, hepatitis B virus surface antibody; HBeAg, hepatitis B virus e antigen; HBeAb, hepatitis B virus e antibody; HBcAb, hepatitis B virus core antibody; MELD, model of end stage liver disease
  3. aReference ranges may vary with patient’s sex, age, pregnancy, etc., and may be different depending on materials and methods used