Characteristic | Univariate | Multivariate | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age | 1.04 (1.03–1.06) |  < 0.001 | 1.028 (1.014–1.043) |  < 0.001 |
Gender | Â | Â | Â | Â |
 Female | 1 |  |  |  |
 Male | 1.23 (0.875–1.73) | 0.234 |  |  |
Ethnic | Â | Â | Â | Â |
 Han | 1 |  |  |  |
 Others | 1.37 (0.94–2) | 0.101 |  |  |
Marital status | Â | Â | Â | Â |
 Married | 1 |  |  |  |
 Others | 0.845 (0.47–1.52) | 0.573 |  |  |
Occupation | Â | Â | Â | Â |
 Worker/clerk | 1 |  |  |  |
 Self-employed/unemployed | 0.979 (0.62–1.55) | 0.929 |  |  |
 Professional and technical personnel | 2.06 (1.23–3.45) | 0.006 |  |  |
 Others | 1.42 (0.934–2.16) | 0.100 |  |  |
Stage | Â | Â | Â | Â |
 I–II | 1 |  | 1 |  |
 III | 2.4 (1.18–4.88) | 0.016 | 2.341 (1.145–4.786) | 0.020 |
 IV | 6.56 (3.33–12.9) |  < 0.001 | 4.593 (2.281–9.248) |  < 0.001 |
Pathological | Â | Â | Â | Â |
 Non-keratinizing differentiation | 1 |  | 1 |  |
 Non-keratinized undifferentiated | 1.07 (0.794–1.440) | 0.663 | 1.084 (0.804–1.463) | 0.597 |
 Keratinized and others | 2.27 (0.718–7.150) | 0.163 | 3.130 (0.957–10.236) | 0.059 |
Transfer | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 0.97 (0.580–1.620) | 0.907 |  |  |
Radiotherapy | Â | Â | Â | Â |
 No | 1 |  | 1 |  |
 Yes | 0.368 (0.268–0.505) |  < 0.001 | 0.421 (0.268–0.662) |  < 0.001 |
Chemical therapy | Â | Â | Â | Â |
 No | 1 |  | 1 |  |
 Yes | 0.469 (0.347–0.634) |  < 0.001 | 0.895 (0.581–1.380) | 0.615 |
Targeted therapy | Â | Â | Â | Â |
 No | 1 |  |  |  |
 Yes | 0.986 (0.699–1.390) | 0.938 |  |  |
EBV | Â | Â | Â | Â |
  < 1000 | 1 |  | 1 |  |
  ≥ 1000 | 3.01 (2.22–4.08) |  < 0.001 | 1.982 (1.408–2.792) |  < 0.001 |
BQ | Â | Â | Â | Â |
  ≤ 0.13 | 1 |  |  |  |
  > 0.13 | 0.907 (0.581–1.420) | 0.669 |  |  |
LAR | Â | Â | Â | Â |
  ≤ 6.15 | 1 |  | 1 |  |
  > 6.15 | 4.41 (3.22–6.04) |  < 0.001 | 2.009 (1.408–2.712) |  < 0.001 |
NLR | Â | Â | Â | Â |
  ≤ 4.84 | 1 |  | 1 |  |
  > 4.84 | 2.61 (1.83–3.71) |  < 0.001 | 1.521 (1.015–2.278) | 0.042 |
PLR | Â | Â | Â | Â |
  ≤ 206.33 | 1 |  | 1 |  |
  > 206.33 | 2.35 (1.73–3.19) |  < 0.001 | 1.712 (1.202–2.438) | 0.003 |