Fig. 4
From: Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model
Cell migration and adhesion enhanced in 3D culture system A The migration of CNE-1 cells cultured in the three systems at 0, 3, 6, 9,12 and 24 h after scratch was significantly different (n = 3). B Migration capability of CNE-1 cells in each group detected by transwell assay. C The wound elosure rate in three groups at each time point was calculated by Image J software (n = 3, *P < 0.05). The cell migration rate of cells in the 3D groups were significantly faster than that in 2D. D The number of migratory cells in each group (n = 3, *P < 0.05). E, F Western blot analysis of E-cadherin, Vimentin, N-cadherin, Slug, ZEB-1 and Integrin β1 expression in cells of each group