Fig. 5
From: Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model
Cell proliferation was enhanced and G1 phase arrest occurred in 3D culture system A Cell colony formation in each group on day 1, 3, 5 and 7 (scale bar 100 μm). B, C Comparison of plating efficiency and colony diameter of CNE-1 cells cultured in three systems (n = 3, *P < 0.05). D The flow cytometry histogram of CNE-1 cells. The cell cycle distribution of CNE-1 cells in 3D groups arrested at G1 phase. E Western blot analysis of Cyclin E1, Cyclin D1 and CDk4 in three groups