Molecular mechanism of circRNAs in drug resistance in renal cell carcinoma

Table 1 Role of circRNAs in regulating renal tumor cells

circRNA	Target	Function	References
circPUM1	miR-340-5p/FABP7	Induced RCC’s progression	ZENG et al. [25]
circ‐ZNF609	miR‐138‐5p/FOXP4	Induced RCC’s progression	Xiong et al. [26]
circPTCH1	miR-485-5p/MMP14	Induced RCC’s progression	Liu et al. [27]
circPCNXL2	miR‐153/ZEB2	Induced RCC’s progression	Zhou et al. [28]
circRNA_001287	miR-144/CEP55	Induced RCC’s progression	Feng et al. [29]
circRNA SCARB1	miR- 510-5p/SDC3	Induced RCC’s progression	Sun et al. [30]
circTLK1	miR-136-5p	Induced RCC’s progression	Li et al. [31]
cRAPGEF5	miR-27a-3p/TXNIP	Suppressed RCC’s progression	Chen et al. [36]
hsa-circ-0072309	miR-100/PI3K/AKT and mTOR	Suppressed RCC’s progression	Tao et al. [37]
circ‐AKT3	miR‐296‐3p/E‐cadherin	Suppressed RCC’s progression	XUE et al. [38]
circUBAP2	miR-148a-3P/FOXK2	Suppressed RCC’s progression	SUN et al. [39]
circHIPK3	miR-637	Suppressed RCC’s progression	Li et al. [40]
hsa_circ_0035483	hsa-miR-335/CCNB1	Enhanced RCC’s resistance to gemcitabine	Yan et al. [57]
circSNX6	miR-1184/GPCPD1	Enhanced RCC’s resistance to sunitinib	Huang et al. [58]
circRNA-001895	miR-296-5P/FOX2	Enhanced RCC’s resistance to sunitinib	Tan et al. [59]
circEHD2	miR-4731-5p/ABCF2	Enhanced RCC’s resistance to sunitinib	Li et al. [61]
circME1	malic enzyme 1	Enhanced RCC’s resistance to sunitinib	Zhang et al. [63]

ISSN: 1475-2867