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Table 1 Expression of c-Rel, p50 and p65 in different cervical tissues

From: Transcription factor c-Rel regulated by E5 affects the whole process after HPV16 infection through miR-133a-modulated feedback loop aim at mir-379-369 cluster

Category

Cervix without lesion

LSIL

HSIL

invasive carcinoma

χ2

P

c-Rel

 

51

22

26

116

  

33

10

6

36

  

 + 

6

5

3

35

  

 +  + 

8

5

8

28

19.873

 < 0.001

 +  +  + 

4

2

9

17

  

Positive rate (%)

35.3

54.5

76.9

69

  

NF-ĸB p65

30

10

13

40

  

 + 

11

9

4

51

  

 +  + 

6

1

5

16

16.356

0.011

 +  +  + 

4

2

4

9

  

Positive rate(%)

41.2

54.5

50

65.5

  

NF-ĸB p50

31

11

9

31

  

 + 

14

5

4

62

  

 +  + 

5

5

6

16

17.205

0.001

 +  +  + 

1

1

7

7

  

Positive rate(%)

39.2

50

65.4

73