Fig. 1
From: NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells
Effect of MR438 on the in vitro radiosensitivity of medulloblastoma stem-like cells. A Representative images of the colony formation assay using methylcellulose for DAOY-MS treated with tuftsin and MR438 at 0 and 2 Gy. B Tumor radiosensitivity factors: alpha, SF2 and DMF2 were calculated after exposition to tuftsin and MR438 from fitting curves C, D, E; the significance for DMF2 and each point of fitting curves were given for each condition in comparison to CTL. C, D, E. Representation of clone numbers after irradiation at 2, 4, 6 and 10 Gy (1*105 cells/well for DAOY-MS and 2*105 cells /well for D283-MS and D341-MS). MS Medullosphere, SF2 Surviving fraction at 2 Gy, DMF2 Dose modified factor at 2 Gy. *p < 0.05 versus 0 Gy, n = 6