Fig. 2From: NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cellsEffect of MR438 on tumor growth and mouse survival after irradiation with heterotopic xenografts. The percentage of tumor growth of DAOY A, D283-Med C and D341-Med E after radiation (5 × 2 Gy) and/or administration of MR438 or tuftsin (10 mg/kg) was calculated from tumor size before treatment as a reference. Survival fractions were represented for DAOY B, D283-Med D and D341-Med F using the maximal tumor size of 1000 mm3 as endpoint. *p < 0.05 versus CTL and #p < 0.05 versus RT, n = 6Back to article page