Ursolic acid: a natural modulator of signaling networks in different cancers

Table 2 List of UA derivates having anti-cancer activity

Derivatives	Modification site	Anticancer activity	Cell line	References
UA1-UA8	C-28	Antiproliferative activity	MCF-7, Hela, and A549	[11]
UA11b, UA7b	C-28	Cell cycle arrest, HIF1- α expression	SMMC-7721 and HepG2	[12]
FZU3010	C-28	Proliferation inhibition, Induction of apoptosis	SUM149PT, HCC1937	[14]
UA1a-2c	C-3	Apoptosis, Cell cycle arrest	VERO, HepG2	[16]
UA232	C-3, C-28	Induction of apoptosis	A549, H460, MCF-7, HeLa	[17, 18]

ISSN: 1475-2867