Table 2 In vitro Antioxidant activities of EOs and isolated compounds
From: Natural essential oils as a new therapeutic tool in colorectal cancer
Type of EO | Tested cell lines | Results | Refs. |
|---|---|---|---|
Allium roseum bulb EO | HT-29 CaCo-2 | ↓Production of superoxide anion | [99] |
Cinnamaldehyde Cinnamon bark extract | HCT-116 HT-29 FHC | ↑Nrf2, ↑cellular glutathione ↓Oxidative stress | [142] |
Thymol | HT-29 | ↑ Protection of the colonic epithelium against oxidative DNA damage | [145] |
Geraniol | HT-29 | ↑Protection from DNA methylation damage | [145] |
Carvacrol Thymol | Caco-2 | ↑Antioxidant properties against DNA strand breaks | [146] |
Fennel (Foeniculum vulgare) EO | HCT-116 | ↑Cell viability, ↑Antioxidant properties ↑DNA protection | [122] |
EO from Myrica rubra leaves | Caco-2 | ↑Selective pro-oxidative effect on cancer cells | [147] |
Thymoquinone | DLD-1 | ↑Pro-oxidative effects ↑Apoptosis | [126] |
Carvacrol | Caco-2 | ↑Pro-oxidative effects at high doses ↑Antioxidant effects at low concentrations | [150] |