METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

Table 1 Relationship between METTL3 and AKR1B10 expression and the clinicopathological characteristics in CCA tissue microarray

Tumor	METTL3 (n = 60)		χ²	P value	AKR1B10 (n = 44)		χ²	P value
Tumor	Low	High	χ²	P value	Low	High	χ²	P value
Age			0.06787	0.7945			1.245	0.2645
< 60	16	18			15	13
≥ 60	14	12			5	11
Gender			0.2820	0.5954			2.146	0.1430
Female	10	13			12	8
Male	20	17			8	16
TNM stage			4.565	0.03263			1.426	0.2324
T1–T2	27	19			18	17
T3–T4	3	11			2	7
Metastasis			1.404	0.2361			0.3536	0.5521
Yes	0	3			1	1
No	30	27			19	23
Relapse			0.1042	0.7469			0.4596	0.4978
Yes	24	24			15	21
No	6	6			5	3
Greatest tumor diameter (cm)			0.06944	0.7921			0.4016	0.5263
< 5	11	13			8	13
≥ 5	19	17			12	11
Tumor-free survival (month)			0.6027	0.4376			0.1291	0.7194
< 4	12	16			12	12
≥ 4	18	14			8	12

ISSN: 1475-2867