Skip to main content
Fig. 5 | Cancer Cell International

Fig. 5

From: The anterior gradient homologue 2 (AGR2) co-localises with the glucose-regulated protein 78 (GRP78) in cancer stem cells, and is critical for the survival and drug resistance of recurrent glioblastoma: in situ and in vitro analyses

Fig. 5

Inhibition of AGR2 exon 2B in conjunction with the clinically relevant drugs temozolomide (TMZ) and irinotecan (IR). A A schematic diagram showing the treatment protocols and the IC50 values. B Immunofluorescence images for treated cells at day 5/6. AGR2 is shown in red and DAPI in blue, and images were taken at 20x. C Barographs displaying the survival fractions of the primary cell lines following individual and co-treatments using siRNA against AGR2 exon 2B with temozolomide or with irinotecan. The error bars represent errors between counts for three independent experiments. The connective lines indicate a significant T-test difference at p < 0.05

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us