Fig. 8

Mifepristone inhibits the adhesion, migration, and invasion capacity of all five HGSOC cell lines despite basal capabilities. HGSOC cells were treated with 20 µM of MF for 72 h prior to plating. Panels A[i–iii] and B[i, ii] represent adhesion assays to fibronectin. Panels A[iv–vi] and B[iii, iv] represent Boyden chamber migration assays. Panels A[vii–ix] and B[v–vi] represent Boyden chamber invasion assays. Data shown represents the mean ± s.e.m. For panels A[i–iii] and B[i, ii], **P < 0.01, and ***P < 0.001 compared to Vehicle. Vehicle (closed bars), MF (open bars). Statistical analysis was done using two-way ANOVA followed by Bonferroni’s test. For panels A[iv–ix] and B[iii–vi], *P < 0.05, **P < 0.01 compared to Vehicle. Statistical analysis was done using student t-test