Table 1 Changes in HER3 expression at initial diagnosis and at recurrence
From: Changes in HER3 expression profiles between primary and recurrent gynecological cancers
HER3-high | H-score, median (IQR) | |||||
|---|---|---|---|---|---|---|
At initial diagnosis | At recurrence | p | At initial diagnosis | At recurrence | p | |
Ovarian cancer (N = 40) | 27 (67.5%) | 32 (80.0%) | 0.20 | 120 (62.5–172.5) | 160 (90–260) | 0.004 |
Endometrial cancer (N = 32) | 15 (46.9%) | 22 (68.8%) | 0.08 | 65 (30–140) | 100 (60–170) | 0.08 |
Cervical cancer (N = 14) | 12 (85.7%) | 12 (85.7%) | 1.00 | 122.5 (88.75–190) | 180 (132.5–250) | 0.19 |
Total (N = 86) | 54 (62.8%) | 66 (76.7%) | 0.046 | 97.5 (42.5–170) | 135 (86.25–220) | < 0.001 |