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Fig. 1 | Cancer Cell International

Fig. 1

From: Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-Coenzyme A synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis

Fig. 1

HSP27 is highly expressed in GBM and is associated with a poor prognosis. A, B The expression features in GBM subtypes were examined using the The Cancer Genoma Atlas and the Chinese Glioma Genome Atlas datasets. TCGA-seq and CGGA-seq data sets were used to estimate the correlation between HSP27 mRNA expression and tumor grade according to the World Health Organization. C Western blotting to detect the expression of HSP27 in normal tissues and tumor tissues. D Immunohistochemistry staining in normal and tumor tissues, the upper scale is 100 μm, and the lower scale is 50 μm. E Western blotting to detect the expression of HSP27 in different cell lines. Statistics are expressed as Mean ± S.E.M. NSP > 0.05, ****P < 0.0001

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