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Fig. 4 | Cancer Cell International

Fig. 4

From: Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-Coenzyme A synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis

Fig. 4

Knockdown of HSP27 promotes ferroptosis in GBM cells. A, B JC-1 detects mitochondrial potential changes at a scale of 100 μm. C–E Transfection with lentivirus and changes in MDA levels under different drug treatments. F Transmission electron microscopy (TEM) facilitates observation of changes in mitochondrial morphology before and after lentiviral transfection. G, H Detection of LDH release rates under different treatment methods. The statistical analysis showed the following: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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