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Fig. 4 | Cancer Cell International

Fig. 4

From: Tetrahydrocurcumin regulates the tumor immune microenvironment to inhibit breast cancer proliferation and metastasis via the CYP1A1/NF-κB signaling pathway

Fig. 4

Transcriptomic analysis and molecular docking of THC in breast cancer cells. A Heatmap depiction of differentially expressed genes between different treated groups in 4T1 cells. B KEGG analysis of representative signaling pathways enrichment between different treated groups in 4T1. C Heatmap depiction of differentially expressed genes of Cytochrome P450 enzyme metabolic system signaling pathways. D After different concentrations of THC were stimulated, the CYP1A1, NF-κb, iκBa, phosphorylated iκBa and PD-L1 protein expression was verified by Western Blot assay in MCF-7 and 4T1cells. E: Molecular binding mode of THC and P4501A1 protein

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Cancer Cell International

ISSN: 1475-2867

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