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Table 3 Diagnostic Accuracy of IHC Testing for Detection of the BRAFV600E Mutation in the 42 studied melanocytic neoplasms in reference to CAST-PCR results

From: BRAFV600E mutational status assessment in cutaneous melanocytic neoplasms in a group of the Egyptian population

Diagnostic Accuracy

IHC BRAF V600 interpretation

Positive vs Negative (test 1)

(Absent + Heterogeneous) vs (Homogenous) (test 2)

Sensitivity

66.7%

66.7%

Specificity

73.3%

88.2%

PPV

72.22%

72.22

NPV

71.43

100%

Diagnostic accuracy

69.9%

77.3%

  1. PPV Positive predictive value, NPA negative predictive value