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Table 4 Comparison of IHC results according to bleaching with CAST-PCR results for the detection of the BRAF V600E mutation in the 42 studied melanocytic neoplasms using the chi-square test

From: BRAFV600E mutational status assessment in cutaneous melanocytic neoplasms in a group of the Egyptian population

IHC results in relation to CAST-PCR

Bleaching status

Total

No bleaching

Prior bleaching

True negative

10

13

23

True positive

3

5

8

False positive

4

4

8

False negative

3

0

3

Total

20

22

42

X2 P(MC)

3.803 0.350 NS

  1. MC Monte Carlo significance test, NS Non significant