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Fig. 1 | Cancer Cell International

Fig. 1

From: A review on the role of long non-coding RNA and microRNA network in clear cell renal cell carcinoma and its tumor microenvironment

Fig. 1

The regulatory mode between lncRNA and miRNA. a LncRNA acts as a sponge for miRNA, which prohibits the binding between miRNA and its targets. b LncRNA can be digested to produce miRNA and influence the transcriptional expression of downstream genes. c MiRNA can induce the degradation of lncRNA via binding to lncRNAs, and eventually suppress the mRNA levels of target genes. d LncRNA can competitively interact with the target genes of miRNA

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