Table 4 LncRNA/miRNA/mRNA axis in ccRCC drug resistance
LncRNA | Therapy | Mechanism | Resistance | Refs. |
|---|---|---|---|---|
LINC00461 | Sunitinib | miR-942/SALL1, METAP1, DCAF11 | Enhance | [181] |
SARCC | Sunitinib | miR-143-3p/AKT, MMP13, K-RAS, p-ERK | Weaken | [182] |
ARSR | Sunitinib | miR-34/AXL, miR-449/c-MET | Enhance | [183] |
HOTAIR | Sunitinib | miR-17-5p/Beclin1 | Enhance | [184] |
ADAMTS9-AS2 | Cisplatin and 5-Fluorouracil | miR-27a-3p/FOXO1 | Weaken | [21] |
MALAT1 | Sunitinib | miR-362-3p/G3BP1 | Enhance | [37] |
LINC02532 | Radiotherapy | miR-654-5p/YY1 | Enhance | [185] |
GAS5 | Sorafenib | miR-21/Sox5 | Weaken | [129] |
KIF9-AS1 | Sorafenib | miR-497-5p/autophagy signaling | Enhance | [22] |
PLK1S1 | Sorafenib | miR-653/CXCR5 | Enhance | [186] |
NEAT1 | Sorafenib | miR-34a/c-Met | Enhance | [187] |