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Fig. 5 | Cancer Cell International

Fig. 5

From: Chorioallantoic membrane assay revealed the role of TIPARP (2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible poly (ADP-ribose) polymerase) in lung adenocarcinoma-induced angiogenesis

Fig. 5

TIPARP enhances genes related to the remodeling of the extracellular matrix. a. Scatter plot of the mRNA expression comparing the average values of A549-TIPARP cells (n = 3, y-axis) to the average values of A549-GFP cells (n = 3, x-axis). The RNA expression value is shown on a log 2 scale. Green lines indicate a two-fold differences in the expression level. TIPARP, MRC2 and MMP7 are shown in magenta. b. A pathway analysis for upregulated genes (fold-change > 2) in A549-TIPARP cells was performed. The top twelve pathways (P < 0.0001) are shown. Pathways related to the extracellular matrix are shown in red

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Cancer Cell International

ISSN: 1475-2867

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