Table 3 Univariate and multivariate COX regression analysis of 97 gastric cancer samples used in the tissue microarrays

Age

97

1.030 (1.004–1.057)

0.022

1.052 (1.015–1.090)

0.006

Gender

97

 Male

74

Reference

 Female

23

1.070 (0.617–1.857)

0.809

T stage

97

 T1

9

Reference

 T2

17

1.441 (0.373–5.574)

0.596

0.883 (0.172–4.536)

0.881

 T3

46

3.515 (1.076–11.486)

0.037

1.234 (0.280–5.446)

0.781

 T4

25

9.291 (2.754–31.351)

 < 0.001

2.270 (0.471–10.936)

0.307

N stage

97

 N0

27

Reference

 N1

14

0.680 (0.266–1.737)

0.420

0.751 (0.239–2.356)

0.624

 N2

25

1.547 (0.788–3.040)

0.205

1.348 (0.605–3.005)

0.465

 N3

31

2.793 (1.492–5.228)

0.001

2.058 (0.816–5.192)

0.126

M stage

97

 M0

84

Reference

 M1

13

8.343 (4.140–16.812)

 < 0.001

5.224 (1.856–14.704)

0.002

Pathologic stage

96

 II

23

Reference

 II–III

28

1.293 (0.678–2.463)

0.435

 III

45

1.029 (0.559–1.895)

0.927

Differentiation

97

 Poorly

49

Reference

 Moderate

38

0.683 (0.404–1.155)

0.155

 Well

5

0.466 (0.143–1.517)

0.205

 Unknown

5

1.501 (0.586–3.847)

0.398

Tumor diameter(cm)

95

  ≤ 3

38

Reference

 3–5

42

1.366 (0.799–2.333)

0.254

1.085 (0.577–2.037)

0.801

  > 5

15

2.259 (1.127–4.531)

0.022

1.108 (0.414–2.962)

0.839

Location

97

 Cardia

2

Reference

 Cardia-corpus

2

79237078.175 (0.000-Inf)

0.996

 Cardia-fundus

12

25653907.317 (0.000-Inf)

0.996

 Fundus

1

1.000 (0.000-Inf)

1.000

 Gastric antrum

65

26698640.929 (0.000-Inf)

0.996

 Gastric corpus

13

33039305.878 (0.000-Inf)

0.996

 Others

2

20383228.678 (0.000-Inf)

0.996

Surgical methods

96

 Distal gastrectomy

64

Reference

 Proximal gastrectomy

16

0.968 (0.487–1.925)

0.926

 Total gastrectomy

14

1.753 (0.904–3.398)

0.097

 Others

2

1.578 (0.382–6.522)

0.529

AFP

78

1.009 (1.002–1.017)

0.018

1.015 (1.006–1.024)

 < 0.001

CEA

78

1.005 (0.995–1.016)

0.313

CA199

78

1.000 (0.999–1.002)

0.578

CA153

77

1.010 (0.987–1.033)

0.406

CA125

77

1.000 (0.994–1.007)

0.954

H pylori infection

74

 ( +)

37

Reference

 (−)

37

1.205 (0.699–2.076)

0.503

IOD of BTG2

97

1.000 (0.986–1.015)

0.969