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Table 3 Mutational statuses of primary patient derived and established GBM cell lines

From: Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis

GBM cell line

IDH1 R132H

TP53

EGFR v III

MGMT status

GBM 29

Negative

Mutated

Negative

Unmethylated

GBM 98

Negative

Mutated

Negative

Unmethylated

GBM 42

Negative

Mutated

Negative

Unmethylated

U251

Negative

Mutated

Negative

Methylated

U251N

Negative

Mutated

Not tested

Methylated

U87

Negative

Wild type

Negative

Unmethylated

A172

Negative

Wild type

Negative

Methylated [114]

T98G

Negative

Mutated

Negative

Unmethylated [114]