Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer

Fig. 3

A, B GSVA enrichment analysis demonstrates different KEGG biological pathways among three distinct clusters, in which yellow and blue represent activated and inhibited pathways, respectively. C Heatmap for differential analysis of cancer-related signaling pathways in three clusters. D Boxplot of abundance of immune cells in three clusters based on the RNA-seq meta cohort. E Venn diagram has shown polyamine metabolism related differentially expressed genes (DEGs) between three PAM cluster. F Kaplan–Meier curves of overall survival (OS) for 1224 CRC patients in meta cohort with different geneCluster. G Sankey diagram demonstrates the changes of PAMcluster, geneCluster, PAMscore and survival status. (*P < 0.05; **P < 0.01; ***P < 0.001; ns, non-significant)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us