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Fig. 1 | Cancer Cell International

Fig. 1

From: High anti-tumor activity of a novel alpha-fetoprotein-maytansinoid conjugate targeting alpha-fetoprotein receptors in colorectal cancer xenograft model

Fig. 1

Structures of ABZ981 maytansinoid, ACT-101-ABZ982 and ACT-101-ABZ-1827 conjugates. A Chemical structure of ABZ981 maytansinoid; B Chemical structure of ACT-101-ABZ982 conjugates where the disulfide linkage is dimethylated C Chemical structure of ACT-101-ABZ1827 conjugates where the disulfide linkage is monomethylated. For B and C the toxin is coupled to ACT-101 via a primary amine and n is the number of toxin molecules per protein

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Cancer Cell International

ISSN: 1475-2867

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