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Table 1 Binding of F-ACT-101 to a panel of tumor cell lines (ng/million cells)

From: High anti-tumor activity of a novel alpha-fetoprotein-maytansinoid conjugate targeting alpha-fetoprotein receptors in colorectal cancer xenograft model

Time (hr)

MOLT-4

U937

COLO-205

H522

MCF-7

OVCAR-3

SKOV-3

0

0.0

0.0

0.0

0.0

0.0

0.0

0.0

0.5

8.1

29.5

6.9

55.6

51.0

67.0

31.3

2

19.0

67.1

33.6

27.1

53.6

21.2

9.2

5

LLOQ*

84.3

75.0

71.3

126.0

71.0

16.0

  1. *Results below LLOQ for the assay