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Fig. 6 | Cancer Cell International

Fig. 6

From: Ancient ubiquitous protein 1 (AUP1) is a prognostic biomarker connected with TP53 mutation and the inflamed microenvironments in glioma

Fig. 6

The GSEA analyses the mRNA sequencing between U87MG with scrambled siRNA and U87MG with siAUP1. A The PCA plot showed the transcriptomes of each group were different. B, C The results of the GSEA showed that there were eight significantly increased signalings in the control group, including the increase of REACTIVE_OXYGEN_SPECIES, PEROXISOME, PI3K_AKT_MTOR_SIGNALING, G2M_CHECKPOINT, KRAS_SIGNALING, P53_PATHWAY, E2F_TARGETS, and MYC_TARGETS_V2. Most of them are relative to the proliferation ability

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Cancer Cell International

ISSN: 1475-2867

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