Fig. 7

MiR-3180 represses tumor growth and metastasis in vivo by inhibiting CD36 and SCD1. a Volume and image of xenograft tumors of HepG2 cells infected with lentivirus carrying control shRNA, SCD1 shRNA, or CD36 shRNA and treated with miR-3180 inhibitor. The tumors were measured every 7 days with a Vernier caliper, and tumor volume curves were plotted (n = 6). b Representative immunofluorescence staining of miR-3180 (purple), SCD1 (green) and CD36 (red) in xenograft tumors from (a). c Representative lung tissues and H&E staining of mouse tail vein injected with MHCC-97H cells stably infected as in (a). The number of tumor nodules is presented in the right panel (n = 6). Scale bar: 100 μm **p < 0.01