Fig. 7

ir/4T1-exo treatment enhances GM-CSF, CCL2 production by BMDMs. a GM-CSF b G-CSF level in the culture supernatant of exosomes-treated BMDMs was measured by ELISA. Compared with PBS, **p < 0.01; compared with 4T1-exo, # p < 0.05. c CCL2 level in the culture supernatant of exosomes-treated BMDMs with or without antibody of anti-GM-CF or anti-G-CSF. Compared with isotype IgG, *p < 0.05; **p < 0.01; compared with 4T1-exo, # p < 0.05; compared with ir/4T1-exo, $ p < 0.05. d CCL2 production by BMDMs treated with GM-CSF or G-CSF with or without antibody of anti-GM-CF. Compared with isotype IgG, **p < 0.01; compared with GM-CSF, $ p < 0.05