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Fig. 3 | Cancer Cell International

Fig. 3

From: The inhibitory receptors PD1, Tim3, and A2aR are highly expressed during mesoCAR T cell manufacturing in advanced human epithelial ovarian cancer

Fig. 3

Expression pattern of inhibitory receptors in patient-derived CAR T cells. CAR T cell population positive for TIM3 (A), PD1 (B), and A2aR (C) in EOC patient-derived T cells after activation and transduction vs. healthy controls. The frequency of Ttex(D) and Tpex(E) cells after activation and transduction of EOC patient-derived T cells vs. healthy controls. Data from healthy donors (n = 30) and EOC patients (n = 30) were analyzed using Mann-Whitney U test (A, B, and D) and Welch’s t-test (C and E). *P < 0.05; **P < 0.01; ***P < 0.001. Data are represented by mean ± SD.

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