Fig. 4
Differential expression of immune inhibitory receptors in different cancer stages during CAR T cell manufacturing. Cell surface expression levels of TIM3 (A), PD1 (B), A2aR (C), and the frequency of Tpex(D) and Ttex(E) cells at different steps of CAR T cell manufacturing process for different stages of EOC. Data from stage III patients (n = 18) and stage IV patients (n = 12) were analyzed using Welch’s t-test. *P < 0.05; **P < 0.01; ***P < 0.001. Data are presented by mean ± SD.