Fig. 2
From: Melatonin blunted the angiogenic activity in 3D colon cancer tumoroids by the reduction of endocan
Monitoring protein levels of endocan and VEGF using the western blot technique (A-B). Treatment with melatonin with doses of 4 and 10 mM significantly reduced endocan levels within the tumoroids after 48 h compared to the non-treated tumoroids. Based on the data, melatonin did not alter protein levels of VEGF in 4 and 10 mM melatonin groups compared to the control tumoriods (n = 3). One-Way ANOVA with Tukey post-hoc analysis. *p < 0.05 and **p < 0.01