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Fig. 5 | Cancer Cell International

Fig. 5

From: MFI2 upregulation promotes malignant progression through EGF/FAK signaling in oral cavity squamous cell carcinoma

Fig. 5

MFI2 promotes cell proliferation and migration through the EGF/pFAK signaling pathway. A Western blot of the MFI2 and pFAK expression in transfected KOSC3 cells. β-Actin was used as a loading control. MFI2-knockdown KOSC3 cells were treated with EGF (30 ng/ml). After transfection for 72 h, B cell proliferation and D migration were analyzed by CCK8 and Transwell assays, respectively. MFI2-overexpressing KOSC3 cells were treated with PF573228 (10 μM). After transfection for 72 h, C cell proliferation and E migration were analyzed by CCK-8 and Transwell assays, respectively. The results are representative of three independent experiments (*p < 0.05, **p < 0.01, ***p < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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