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Table 2 The clinicopathological characteristics related to the expression of MFI2 in 115 samples of OSCC

From: MFI2 upregulation promotes malignant progression through EGF/FAK signaling in oral cavity squamous cell carcinoma

Patient categories

Case number

MFI2 expression level

 

Low (%)

High (%)

p value

Sex

 Male

103

56 (54.4)

47 (45.6)

0.404

 Female

12

5 (41.7)

7 (58.3)

 

Agea

 

51.0 ± 10.8

(78.3, 22.5)

52.8 ± 13.4

(79.8, 20.3)

0.550

Tumor classification

 T1–T2

58

32 (55.2)

26 (44.8)

0.644

 T3–T4

57

29 (50.9)

28 (49.1)

 

Node classification

 0

55

36 (65.5)

19 (34.5)

0.011b

 > 0

60

25 (41.7)

35 (58.3)

 

Overall TNM stage

 I–II

34

24 (70.6)

10 (29.4)

0.015b

 III–IV

81

37 (45.7)

44 (54.3)

 

ENE

 No

84

48 (57.1)

36 (42.9)

0.147

 Yes

31

13 (41.9)

18 (58.1)

 

PNI

 No

59

38 (64.4)

21 (35.6)

0.012b

 Yes

56

23 (41.1)

33 (58.9)

 

Differentiation

 Well + moderately

100

56 (56.0)

44 (44.0)

0.101

 Poorly

15

5 (33.3)

10 (66.7)

 

Tumor depth (mm)

 ≤ 8

44

24 (54.5)

20 (45.5)

0.799

 > 8

71

37 (52.1)

34 (47.9)

 
  1. ENE, extranodal extension; PNI, perineural invasion
  2. aMean ± SD, (maximum, minimum)
  3. bThese are considered statistically significant