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Fig. 1 | Cancer Cell International

Fig. 1

From: WEE1 and PARP-1 play critical roles in myelodysplastic syndrome and acute myeloid leukemia treatment

Fig. 1

Gene expressions of WEE1 and PARP1 in the MDS or AML cell lines. (A, D) The gene expressions of WEE1 and PARP1. The validation of the WEE1 gene by the GEO data (GSE15061) comparing the 164 MDS, 202 AML, and 69 non-leukemia bone marrow samples (control group). (B, E) The gene expressions of WEE1 and PARP1 by the GEO data (GSE4619) comparing the MDS patient group (n = 55; 18 patients had RA, 19 had RARS, 9 had RAEB1, and 9 had RAEB2) and the control group (n = 11). (C, E) The gene expression data of the WEE1 and PARP1 genes by the GEO data (GSE12211) comparing the AML patient group (n = 443), RAEB group (n = 4), and the RAEB-t group (n = 13). Significance was expressed as ***p < 0.001 and ns: not significant

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