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Fig. 14  | Cancer Cell International

Fig. 14 

From: Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinoma

Fig. 14 

Schematic pathway representing the connection between PRKCG with other major genes involved in carcinogenesis. The gene expression levels of oncogenes and corresponding metabolites a PKC γ (b). Hif-1 alpha (c) VEGF (d) AKT (e) RAS (f) RAF (g) MEK (h) ERK (i) Cyclin D (j) SRC (k) SOS (l). VEGFR (m) Grb (n). EGF (o) EGFR (p) PA (q) PLD1 (r) DAG (s) PI3K and (t) TPA were found upregulated (↑) while tumor suppressor genes (u) mTOR and (v) SOCS3 were found downregulated (↓)

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Cancer Cell International

ISSN: 1475-2867

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